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Darkthoryne Asylum follows Melody, a sarcastic girl who finds herself in a bizarre insane asylum. She has amnesia, so she can't remember anything about her past or why she's there. Strange doctors who seem to be keeping secrets, monsters shaped like shadows, patients with supernatural abilities, and mysterious kidnappers are littered throughout the asylum. Will Melody ever uncover the secrets of Darkthoryne Asylum and her past, or will Dr. X ensure she never leaves?